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Entry Inhibitors

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How entry inhibitors work

There are two types of entry inhibitors: CCR5 inhibitors and fusion inhibitors.

HIV uses a chemical called CCR5 to know (recognize) which cells are CD4 cells. CCR5 inhibitors stop HIV from using this chemical to find CD4 cells. If HIV cannot find CD4 cells, then it cannot make copies of itself and go on to infect other cells.

The fusion inhibitor is the other type of entry inhibitor used to HIV treatment. Fusion inhibitors physically block HIV from getting inside CD4 cells. If HIV cannot find CD4 cells, then it cannot make copies of itself and go on to infect other cells.

FDA-approved Entry Inhibitors

For additional information about these HIV products, please review the Important Safety Information.

Brand name Generic name Pharmaceutical company
Fuzeon® (prescribing information) enfuvirtide (T-20) Trimeris and Hoffmann-La Roche
Selzentry™* maraviroc Pfizer
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